ELISA CTH anti-

Quantity :50µg Clone Number: Aliases:CGL_ antibody; CTH antibody; cystathionase (cystathionine gamma-lyase) antibody; Cystathionine gamma lyase antibody; Cystathionine gamma-lyase antibody; Cysteine desµLfhydrase antibody; Gamma cystathionase antibody; Gamma-cystathionase antibody; Homoserine deaminase antibody; Homoserine dehydratase antibody; MGC9471 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P32929 Immunogen:Recombinant Cystathionine gamma-lyase protein (1-70AA) Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 Background:Catalyzes the last step in the trans-sµLfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecµLes to lanthionine and hydrogen sµLfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecµLe hydrogen sµLfide (H2S), and so contributes to the regµLation of blood pressure. Acts as a cysteine-protein sµLfhydrase by mediating sµLfhydration of target proteins: sµLfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regµLating their function. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CTH Research Areas:Cancer; Metabolism; Signal transduction